Vaccine Education Center

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Vaccine Availability Timeline

These dates represent when vaccines first became available. Please note that if you are unsure about having received a vaccine, this table can only tell you whether the vaccine was available, but cannot confirm whether you personally had the vaccine since not everyone in the population was immunized.

Routinely recommended vaccines Vaccines not routinely recommended
1914 – Pertussis vaccine 1798 – Smallpox vaccine
(discontinued use for general population in US 1971)
1926 – Diphtheria vaccine 1885 – First rabies vaccines
1938 – Tetanus vaccine 1896 – Typhoid fever vaccine
1945 – Inactivated influenza vaccine - trivalent
(shot; not routinely recommended)
1927 – Tuberculosis vaccine (BCG)
1948 – Diphtheria, tetanus, and pertussis vaccines combined to form DTP 1930s – Japanese Encephalitis vaccine
1955 – Inactivated polio vaccine (shot) 1935 – Yellow fever vaccine
1960 – Live polio vaccine (oral) 1954 – Anthrax vaccine
1963 – Measles vaccine 1965 – Currently used anthrax vaccine
1967 – Mumps vaccine 1986 – Currently used JE vaccine
1969- Rubella vaccine 1997 – Currently used rabies vaccines
1971 – Measles, mumps and rubella vaccines combined to form MMR 1999-2002 Lyme disease vaccine
(no longer available)
1981 – Hepatitis B vaccine  
1985 – Hib vaccine  
1992 – DTaP vaccine  
1995 – Varicella vaccine  
1995-1996 – Hepatitis A vaccine  
1998 – Rotavirus vaccine (Rotashield®)
(removed from market 2000)
2000 – Pneumococcal conjugate vaccine  
2003 – Intranasal influenza vaccine - trivalent  
2005 – Meningococcal vaccine for adolescents  
2005 – Tdap vaccine for adolescents  
2006 – HPV vaccine for adolescent girls  
2006 – Rotavirus vaccine (RotaTeq®)  
2006 – Shingles vaccine (60 yrs & older)  
2008 – Rotavirus vaccine (RotaRix®)  
2009 – HPV vaccine for adolescent boys  
2013 – Inactivated and intranasal influenza vaccine - quadrivalent  

Reviewed by: Paul A. Offit, MD
Date: April 2013

Materials in this section are updated as new information and vaccines become available. The Vaccine Education Center staff regularly reviews materials for accuracy.

You should not consider the information in this site to be specific, professional medical advice for your personal health or for your family's personal health. You should not use it to replace any relationship with a physician or other qualified healthcare professional. For medical concerns, including decisions about vaccinations, medications and other treatments, you should always consult your physician or, in serious cases, seek immediate assistance from emergency personnel.


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